Why Modern Technology Changes the Effectiveness of Natural Compounds
Natural compounds often have strong potential, but their effectiveness depends on how well the body can absorb them.
Berberine is a perfect example — scientifically well-studied, but naturally limited by poor absorption.
This is where fitosomal technology comes into play, representing one of the biggest innovations in the dietary supplement field in recent years.
What Is Fitosomal Technology?
A fitosome is a form in which plant active compounds are bound to phospholipids, natural components of cell membranes.
The result is:
- easier passage through the intestinal wall
- better absorption
- more efficient cellular uptake
- longer retention in the body
In simple terms, the body recognizes and utilizes the active compound more effectively.
For berberine, this means significantly improved bioavailability compared to conventional forms.
What Does This Mean for Daily Life?
When berberine is absorbed more efficiently, many users notice:
- more stable blood sugar levels
- reduced cravings for sweets
- better appetite control
- steadier energy throughout the day
- easier weight management
It is important to note that no supplement replaces a healthy lifestyle, but a properly formulated product can help the body more easily achieve metabolic balance.
The fitosomal form allows the desired effects with better tolerance and lower doses.
Smart Choice for Metabolic Support
When choosing a dietary supplement, it’s important to consider not just the ingredient, but also the technology behind it.
Our product uses fitosomal berberine combined with other metabolically active ingredients, providing enhanced support for sugar regulation, appetite, and energy as part of a long-term approach to metabolic health.
The real difference often isn’t the ingredient — it’s how the body can use it.
A smart solution for maintaining your glucose levels and metabolic balance
B SMART®
A natural, unique combination that improves blood glucose control and supports metabolic balance.
- Fitosomal Berberine (microscopically encapsulated) – up to 10x better bioavailability*, supports normal glucose levels, cholesterol and triglyceride control, and insulin sensitivity
- Gymnema sylvestre – additional glucose control, reduces sweet cravings
- Chromium – supports macronutrient metabolism and maintains normal glucose levels
5-in-1 Effect:
- supports normal blood glucose levels
- reduces insulin resistance
- decreases sweet cravings
- supports overall metabolism and weight management
- helps combat low-grade chronic inflammation often present in metabolic conditions with insulin resistance
Additional Benefits:
- Vitamin B6 supports protein and glycogen metabolism
- Vitamin D supports immune function and cell protection
- suitable for vegetarians and vegans
- free from gluten, allergens, hormones, additives, and artificial colors
- made in Croatia
- developed by pharmaceutical experts with long-standing experience
Take control of your metabolism.
Sources:
- Toma L, Deleanu M, Sanda GM, Barbălată T, Niculescu LŞ, Sima AV, Stancu CS. Bioactive Compounds Formulated in Phytosomes Administered as Complementary Therapy for Metabolic Disorders. Int J Mol Sci. 2024 Apr 9;25(8):4162. doi: 10.3390/ijms25084162. PMID: 38673748; PMCID: PMC11049841.
- Asghari P, Babaei A, Zamanian N, Eshtivani EN. Berberine’s impact on health: Comprehensive biological, pharmacological, and nutritional perspectives. Metabol Open. 2025 Sep 25;28:100399. doi: 10.1016/j.metop.2025.100399. PMID: 41089338; PMCID: PMC12516553.
- Rondanelli, M., et al. “Berberine phospholipid exerts a positive effect on the glycemic profile of overweight subjects with impaired fasting blood glucose (IFG): a randomized double-blind placebo-controlled clinical trial.” European Review for Medical and Pharmacological Sciences 27 (2023): 6718-6727.
- Wh H, R K, C D, I N, E S, A A. The effect of a 14-day Gymnema sylvestre intervention to reduce sugar intake in people self-identifying with a sweet tooth. Appetite. 2025 Mar 1;207:107871. doi: 10.1016/j.appet.2025.107871. Epub 2025 Jan 23. PMID: 39855349
Pametno rješenje za održavanje vaše razine glukoze i ravnotežu metabolizma
B SMART®
Prirodna, jedinstvena kombinacija koja poboljšava kontrolu glukoze u krvi i pomaže u ravnoteži metabolizma.
- Fitosomalni oblik berberina (unutar mikroskopske kapljice ulja) za do 10 x bolju bioraspoloživost* doprinosi održavanju normalne razine glukoze, boljoj kontroli kolesterola i triglicerida te podržava osjetljivost stanica na inzulin.
- Srebrna svilenica za dodatnu kontrolu glukoze i smanjenje želje za slatkom hranom.
- Krom doprinosi normalnom metabolizmu makronutrijenata i održavanju normalne razine glukoze u krvi.
- Učinak 5 u 1: studije pokazuju kako navedeni sastojci podržavaju normalnu razinu glukoze u krvi, smanjuju inzulinsku rezistenciju, smanjuju žudnju za slatkom hranom, podržavaju ukupan metabolizam što doprinosi boljoj kontroli tjelesne težine te doprinose suzbijanju kroničnih upalnih procesa niskog stupnja u organizmu često prisutnih kod specifičnih metaboličkih stanja praćena inzulinskom rezistencijom.
- Vitamin B6 doprinosi normalnom metabolizmu proteina i glikogena.
- Vitamin D za dodatnu potporu imunološkom odgovoru i zaštitu stanica
- Primjeren za vegetarijance i vegane
- Bez glutena, alergena, hormona, aditiva i umjetnih bojila
- Proizvedeno u Hrvatskoj
- Razvili farmaceutski stručnjaci s iskusnim dugogodišnjim radom u javnoj ljekarni
Preuzmi kontrolu nad svojim metabolizmom.
Izvori:
- Guo J, Chen H, Zhang X, Lou W, Zhang P, Qiu Y, Zhang C, Wang Y, Liu WJ. The Effect of Berberine on Metabolic Profiles in Type 2 Diabetic Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Oxid Med Cell Longev. 2021 Dec
- Zhao F, Pan D, Wang N, Xia H, Zhang H, Wang S, Sun G. Effect of Chromium Supplementation on Blood Glucose and Lipid Levels in Patients with Type 2 Diabetes Mellitus: a Systematic Review and Meta-analysis. Biol Trace Elem Res. 2022 Feb;200(2):516-525. doi: 10.1007/s12011-021-02693-3. Epub 2021 Mar 30. PMID: 33783683.
- Musazadeh V, Kavyani Z, Mirhosseini N, Dehghan P, Vajdi M. Effect of vitamin D supplementation on type 2 diabetes biomarkers: an umbrella of interventional meta-analyses. Diabetol Metab Syndr. 2023 Apr 19;15(1):76. doi: 10.1186/s13098-023-01010-3. PMID: 37072813; PMCID: PMC10114333.
- Rondanelli, M., et al. “Berberine phospholipid exerts a positive effect on the glycemic profile of overweight subjects with impaired fasting blood glucose (IFG): a randomized double-blind placebo-controlled clinical trial.” European Review for Medical and Pharmacological Sciences 27 (2023): 6718-6727.
- 3. Wh H, R K, C D, I N, E S, A A. The effect of a 14-day Gymnema sylvestre intervention to reduce sugar intake in people self-identifying with a sweet tooth. Appetite. 2025 Mar 1;207:107871. doi: 10.1016/j.appet.2025.107871. Epub 2025 Jan 23. PMID: 39855349.
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